The respiratory system is essential to the birds’ performance. It is important not only for oxygen transport, but also for removal of metabolic waste and by-products. A healthy respiratory system can eliminate 80% of the germs inhaled within 1-3 hours. Due to its highly efficient nature and exposure to the external environment, it is easily susceptible to a range of diseases and problems which can insidiously affect the genetic potential of performance livestock.

Sukhjeet Singh Kahlon– Technical Manager, Intracare B.V. The Netherlands

In winters and times of respiratory distress and discomfort, animals spend less time eating and drinking. Essential oil-based products with their unique blend have long been used in livestock farming not only to help alleviate the severity and duration of respiratory problems, but also to help keep animals cool during thermal challenges.

Just mixing of some oils at any concentration does not make an ideal product it requires deep know-how to find a fine balance between active ingredients and supporting elements. When a group of animals require treatment, drinking water application is a responsible and useful option on the condition that the drinking water, the system, and the products are of good quality. Products should be selected which are carefully formulated to meet an optimal balance between solubility, stability, and bioavailability. The active ingredients should be well soluble and highly available to the animal. The supporting elements in formulations help to create a homogenous mixture.

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With this knowledge in hand, very few products have therefore been optimally formulated to be fully soluble in water and is also very well dispersed in on-farm conditions. The product must be immediately solubilized in water upon addition or injection and is fully homogenous in solution. If added to a bulk tank, minimal stirring needs to be required and does not require much external energy inputs such as a mechanical mixer. The selected product should not require the use of warm or hot water to be fully solubilized, as this is oftentimes not practical on the farm. Being completely soluble and consistently dispersed in water, it should have less risk of encouraging biofilm growth and the risk of drinking nipple blockages is also very much reduced.

With its highly soluble and homogenous dispersion properties, product should be selected based on following criterion to helps farmers to:

1 Reduce labour: Selected product can be directly dosed to the drinking system and doesn’t require warm water and/or a pre-solution step. This valuable time can then be used by the farmer for other important management practices.

2 Equal distribution in the drinking water: Homogeneity and uniformity of the flock is an important factor for producers. Therefore, it is equally important that supplementation is also homogenous and uniformly dispersed in the drinking water, reducing the risks of stragglers and non-uniform growth.

3 High quality, well soluble and stable in solution to prevent biofilm: The Selected product should not only be well soluble but should also stay stable in solution. This not only helps to prevent biofilm formation, and the animals consume a continuous, consistent dose thus reducing risks of taste-aversion and decrease in water consumption.

Figure 1: Product A dispersed fully in water (20°C), right – product B with obvious clump forming after dosing in water (20°C)

A lab-scale comparison was conducted to determine the solubility and dispersion aspects of two leading brands from Europe in room temperature water of 20°C. Product-A and Product-B were dropped into tap water at the advised dosages according to the labels. It was observed that product-A had perfect dispersion and did not form clumps or sediments when compared to other competitor products. Even gentle stirring did not manage to completely break the clumps of competitor products and in a drinking line. This could surely lead to nipple blockage and uneven dosing causing an eventual headache for the farmer.

In conclusion, it is important for a drinking-water based nutritional solution to not only be functional, but also have well soluble properties with good homogenous dispersal at farm conditions.

Avian mycoplasmosis, is a contagious respiratory disease that affects poultry, particularly chickens and turkeys. It is caused by various Mycoplasma spp. and can lead to significant economic losses in the poultry industry. Mycoplasmosis is primarily caused by two species of Mycoplasma: Mycoplasma gallisepticum (MG) and Mycoplasma synoviae (MS). These bacteria are responsible for a range of respiratory and systemic infections in birds. These are simplest prokaryotic microorganisms with the ability of self-replication, the most distinguishing characteristic of these bacteria is lack of cell wall. MG is the most common cause of mycoplasmosis in poultry and infected chicken shows a wide variety of symptoms including rales, coughing, nasal discharge, conjunctivitis, reduced feed efficiency, air sacculitis and egg production typically declines with initial infection, then recovers and maintained at a lower level.

AuthorsMycoplasma gallisepticum infection in birds usually takes a long time to manifest and is followed by severe respiratory tract inflammation. In flocks, the disease often goes unnoticed and causes latent infections. According to earlier studies, conditions including high feed density, heat and cold stress, high levels of ammonia, accumulation of feces, fouling of the chicken house, wide temperature variations, and abrupt climatic changes can all contribute to the spread and outbreak of disease.

Virulence factors

Variety of surface polypeptides and lipoproteins of MG plasma membrane are known and have putative function in motility, cytadhesion, surface antigen variation, and nutrient acquisition, all of which are essential virulence factors for MG.

Host- Pathogen interaction

M. gallisepticum attaches itself to the ciliated cells in the respiratory tract of birds using specialized surface proteins. For effective colonization and eventual pathogenesis, the attachment of MG to host cell is utmost important. Once attached, it invades the host cells. The gliding motility of Mycoplasma gallisepticum organisms enables them to enter target tissues and overcome host’s physical defences such respiratory mucus and ciliary activity.

Colonization and Multiplication: Numerous MG cytadhesins and putative cytadhesins have a recognized role in emergence phenotypic variation, which is assumed to be a key virulence component since it appears to facilitate chronic infection and evasion of host immune response. After invading the cells, the bacterium replicates within them. This leads to damage to the host cells, interfering with their normal function.

Inflammatory response: The host’s immune system recognizes the presence of the bacterium and mounts an inflammatory response. This involves the release of various immune cells and inflammatory mediators to combat the infection.

Tissue Damage and Lesions: The inflammation, coupled with the bacterial replication and host immune responses, can lead to damage in the respiratory tissues. This damage may manifest as lesions in the trachea, bronchi, and air sacs.

Transmission

M. gallisepticum can spread within a flock through respiratory secretions, faeces, and contaminated equipment or environment. Some wild bird species, multiage commercial layer flocks, and backyard flocks are potential MG infection reservoirs. The upper respiratory tract and conjunctiva are portals of entry for organism in aerosols or droplets.

The dynamics of MG infection relies heavily on clinically or sub clinically infected carrier birds since Mycoplasma gallisepticum hardly survives outside the host for longer than a few days, yet several studies reported the ability of MG to survive up to several days on contaminated fomite materials (dust, feathers etc) provides important insights on epidemiology of the disease. Some M. gallisepticum strains capacity to develop biofilms may enable them to survive in the environment for longer duration. MG can be transmitted from infected breeder flock to their progeny via transovarian transmission. Some studies concluded that the vertical transmission of MG occurs at the highest rates during the acute phase of disease when the level of MG is at peak in respiratory tract and declines subsequently as the post infection interval lengthens.

Carrier State: Some birds may become carriers of M. gallisepticum, meaning they harbour the bacterium without showing overt signs of illness. These carriers can serve as a source of infection for other birds.

Symptoms

Respiratory Distress: Birds infected with mycoplasmosis often exhibit respiratory distress, characterized by coughing, sneezing, nasal discharge, and wheezing.

Reduced Egg Production: In laying hens, mycoplasmosis can lead to a decrease in egg production, as well as a decrease in egg quality.

Swollen Eyes and Sinusitis: Infected birds may develop swollen eyes and sinusitis, along with a discharge from the eyes.

Conjunctivitis: The infection can lead to inflammation of the conjunctiva, causing redness and discharge from the eyes.

General Weakness: Infected birds may exhibit lethargy, decreased appetite, and a drop in overall activity levels.

Diagnosis

Accurate diagnosis of mycoplasmosis is crucial for effective management. It is typically achieved through a combination of clinical signs, post-mortem examinations, and laboratory tests. These tests may include serology (blood tests), PCR (polymerase chain reaction), and bacterial isolation from affected tissues.

Prevention and Control

Biosecurity Measures: Implement strict biosecurity measures to prevent the introduction and spread of mycoplasmosis. This includes limiting visitor access, maintaining separate footwear and clothing for workers, and disinfecting equipment and facilities regularly.

Vaccination: There are vaccines available for both MG and MS, determine the most appropriate vaccination schedule for your poultry.

Cleanup Programs: Use of appropriate molecule for effective cleaning up of mycoplasmal infection prior to vaccination may provide better results.

Minimize Stress: Stress weakens the immune system, making birds more susceptible to infections. Provide a low-stress environment by ensuring proper nutrition, ventilation, and living conditions.

Surveillance: Regularly monitor your flock for any signs of illness. Early detection allows for prompt intervention and reduces the spread of the disease.

Authors:

Reference:
Beaudet, J., E. R. Tulman, K. Pflaum, X. Liao, G. F. Kutish, S. M. Szczepanek, L. K. Silbart, and S. J. Geary. 2017. Transcriptional profiling of the chicken tracheal response to virulent Mycoplasma gallisepticum strain Rlow. Infect. Immun. 85: e00343- 17.
Browning, G.F., A.H. Noormohammadi, and P.F. Markham. 2014. Identification and characterization of virulence genes in mycoplasmas. In: Mollicutes – Molecular Biology and Pathogenesis. G.F. Browning and C. Citti, ed. Caister Academic Press, Norfolk, UK. 77–90.
Boguslavsky, S., D. Menaker, I. Lysnyansky, T. Liu, S. Levisohn, R. Rosengarten, M. Garcia, and D. Yogev. 2000. Molecular characterization of the Mycoplasma gallisepticum pvpA gene which encodes a putative variable cytadhesin protein. Infect Immun. 68:3956–3964.
Evan, J. D., S. A. Leigh, S. L. Branton, S. D. Collier, G. T. Pharr, and S. M. D. Bearson. 2005. Mycoplasma gallisepticum: current and developing means to control the avian pathogen. J. Appl. Poult. Res. 14:757–763.
Hochachka, W. M., and A. A. Dhondt. 2000. Density-dependent decline of host abundance resulting from a new infectious disease. Proc. Natl. Acad. Sci. USA. 97:5303–5306.
Indikova, I., M. Vronka, and M.P. Szostak. 2014. First identification of proteins involved in motility of Mycoplasma gallisepticum. Vet Res. 45:99.
Ishfaq, M., W. Zhang, W. Hu, S. Waqas Ali Shah, Y. Liu, J. Wang, Z. Wu, I. Ahmad, and J. Li. 2019. Antagonistic effects of Baicalin on mycoplasma gallisepticum-induced inflammation and apoptosis by restoring energy metabolism in the chicken lungs. Infect. Drug Resist. 12:3075–3089.
Jan, G., C. Brenner, and H. Wroblewski. 1996. Purification of Mycoplasma gallisepticum membrane proteins p52, p67 (pMGA), and p77 by high‐ performance liquid chromatography. Protein Expr Purif. 7:160–166.
Keeler, C.L., Jr., L.L. Hnatow, P.L. Whetzel, and J.E. Dohms. 1996. Cloning and characterization of a putative cytadhesin gene (mgc1) from Mycoplasma gallisepticum. Infect Immun. 64:1541–1547. 130.
Ley, D. H. 2003. Mycoplasma gallisepticum infection. Pages 722–743 in Diseases of Poultry. Y. M. Saif, ed. 11th ed. Iowa State Press, Ames, IA.
Mikaelian, I., D.H. Ley, R. Claveau, M. Lemieux, and J.P. Berube. 2001. Mycoplasmosis in evening and pine grosbeaks with conjunctivitis in Quebec. J Wildl Dis. 37:826–830.
Miyata, M. and D. Nakane. 2014. Gliding mechanism of the Mycoplasma pneumoniae subgroup. In: Mollicutes – Molecular Biology and Pathogenesis. G.F. Browning and C. Citti, eds. Caister Academic Press, Norfolk, UK. 237–253.
Raviv, Z., S. Callison, N. Ferguson‐Noel, V. Laibinis, R. Wooten, and S.H. Kleven. 2007. The Mycoplasma gallisepticum 16S‐23S rRNA intergenic spacer region sequence as a novel tool for epizootiological studies. Avian Dis. 51:555–560.
Szczepanek, S.M. and L.K. Silbart. 2014. Host immune responses to mycoplasmas. In: Mollicutes – Molecular Biology and Pathogenesis. G.F. Browning and C. Citti, eds. Caister Academic Press, Norfolk, UK. 273–288.
Zimmermann, C.U. 2014. Current insights into phase and antigenic variation in mycoplasmas. In: Mollicutes – Molecular Biology and Pathogenesis. G.F. Browning, and C. Citti, eds. Caister Academic Press, Norfolk, UK. 165–196.

Sweden-based specialty chemicals innovator Perstorp has built and commissioned a state-of-the-art, ISCC Plus certified, plant in western India, to meet growing market demand for Penta chemicals. Located in Sayakha, Bharuch, in the state of Gujarat, the facility is officially inaugurated on Feb. 20.

Perstorp logoThis is the largest investment in Asia so far, in Perstorp’s history. It will further strengthen Perstorp’s position as a sustainable and reliable partner in the region of Asia,” noted Gorm Jensen, Perstorp’s Executive Vice President Commercial & Innovation. “This plant will increase the availability and reliability of products for current, as well as new customers, reducing lead times with about 50% for Asian customers. It is strategically located close to ports, rails and roadways. This will help to ensure that Perstorp can supply products effectively throughout India and across all of Asia. At the same time, the plant is well positioned to also export products globally.”

In Sayakha Perstorp will produce a Penta product mix including Perstorp’s renewable based, ISCC PLUS-certified grade, Voxtar™, as well as offering Penta Mono and Calcium Formate. The plant will use renewably sourced raw materials as well as a hybrid source of electricity. Voxtar™ is a renewable based counterpart to Penta. Based on a traceable mass balance concept, Voxtar™ is designed to reduce the carbon footprint throughout the value chain and to support sourcing of renewable and recycled raw materials. As Voxtar™ is chemically identical to Penta, it provides customers with the same quality and performance as their fossil counterpart.”

Perstorp already produces Penta in Sweden, Germany and the United States, but this investment will represent a significant expansion of its global production capacity. At the new site, Perstorp has the capacity to annually produce 40,000 metric tonnes of Pentaerythritol and 26,000 metric tonnes of calcium formate.

“This is a major investment that Perstorp has been projecting for several years and we are very excited to inaugurate this state-of-the art plant and better serve our current and future customers”, Vinod Tiwari, Managing Director and General Manager India concludes.

The site covers nearly 115,000 square meters (1.23 million square feet) and will employ about 120 people.

Source: Perstorp

Synopsis: CRD & CCRD is a severe & chronic yearlong/anytime infection in all age groups of poultry Poultry Farmers can be victorious and at their ease by overcoming this stubborn infection with the scheduled CRD – C-CRD prevention program with the effective usage of anti-mycoplasma solution through feed and/or through drinking water.

Poultry CRD author pic
Dr. Ram Moorthy D
CEO, Geenat
E: rammoorthyd@gmail.com
W: www.geenat.co.in
Phone: +91 93446 42382

CRD – Round the clock with infection

CRD infection is caused by Mycoplasma gallisepticum (MG).

When MG gets complexed it forms C-CRD – Complexed CRD with either of the following reasons

1. C-CRD of Bacterial Infection – MG with Escherichia coli (E. coli) infection

2. Environmental C-CRD MG with contaminated air (High ammonia level)

3. Viral infections – MG with Viral Infection

C CRD 

Complexed-CRD (CCRD) is caused by the stubborn infection of Mycoplasma Gallisepticum (MG) ‘clubbed with either E. coli/Ammonia/Viral infection.

CCRD can affect all formats of poultry in anytime in all formats of Poultry in any age- Broiler, Layer & Breeder
It’s highly prevalent during extreme weather conditions like summer or winter.

However, CCRD is round the clock infection with low mortality and high morbidity, which can suppress immune system of the birds.

Sub-clinical level infections are frequent which can cause severe Production loss with high feed intake & low production.

Acute infections can cause an outbreak.

Birds’ Respiratory system – A complex one

CCRD -Complex CRD – CCRD is crucial & vulnerable when MG combines with respiratory infections in Poultry.

Bacterial CCRD – MG + clubs with Bacteria – E. Coli to form Colibacillosis.
Symptoms

  • Diarrhoea
  • High Feed consumption & High mortality if not treated well in time

Non infectious CCRD MG with contaminated air (Ammonia Gas)
This CCRD causes ‘Acidic blood’.

Birds’ Excessive inhalation of Ammonia & Low oxygen intake, increase the levels of Carbonic Acid in the blood causing Acidic Blood condition.

Symptoms

  • Panting, High-water intake, crowding (hurling together)
  • Feather loss, High stress & Sudden deaths

Poultry Panting, Feather loss

Viral C-CRD – MG + Viral infection (ILT & IB are common)
MG clubs with ILT – Infectious Laryngotracheitis virus & IB (Infectious Bronchitis) – Common.
MG with other viral infections of Avian Influenza, New castle disease & Infectious Coryza

Viral C - CRD

CCRD – Disease Stages

CCRD Stage 1 – CCRD infects Trachea – URT –Upper Respiratory Tract infection

CCRD Stage 2 – Forms Septicaemia – CCRD Infection spreads into Circulatory system

CCRD Stage 3 – Airsacculitis – CCRD Infection becomes intense & Chronic when it gets deep into the LRT – Lower Respiratory Tract

CCRD Stages

CCRD Stage 4 with clinical symptoms
There will be notable clinical symptoms of coughing, swollen eyes, noisy & difficulty in breathing, change in colour of the comb – blackish red, severe production loss in laying hens with high feed intake.

CCRD Stage

With the above clinical symptoms, if CCRD is not treated properly can lead to severe economic losses including acute mortality (sudden deaths of the birds).

CRD & C-CRD – Prevention Program

They are better to control than to treat through feed & through drinking water.

Broiler, Layer & Breeder –

The choice of drug to prevent mycoplasma infection – Macrolide group of antibiotics.

Administration – Through feed.

For treatment to control the mortality

  • Macrolide and/or Aminoglycoside group of antibiotics
  • Can be administered through feed, water & through injection (s/c sub cutaneous injection and adult birds through I/M – Intra Muscular)

Dosage can be followed as per the advice of the consulting vets

Complimenting the CRD – C-CRD Prevention program

This Prevention program can be double assured by clubbing the alternative medicines

  • Phytochemical solutions as extracts – Gingerol, Curcumin, Solanum trilobatum as expectorants, immune booster and blood purifier.
  • Essential oils combination – can be administered through drinking water.
  • Acidifier through feed and or drinking water.
  • Permitted AGPs

AGPs dosage can be followed by the consulting vets’ advice.

Withdrawal of AGPs should be strictly followed to ensure food safety measures.

Summary

CRD & C- CRD (MG – Mycoplasma gallisepticum) infection can cause great economic losses if not attended properly.

However, CRD & C-CRD infection can be prevented & cured in all formats of poultry (Broiler, commercial Layer & breeder) with systematic usage of combination of Anti-mycoplasma drugs with the alternative medicines ‘discussed here.


Previous article by author: Soya Alternatives

Bengaluru, India (February 7, 2024) – NOVUS recently named Dr. Manish Kumar Singh its new regional director for NOVUS in South Central Asia. In this role, Dr. Singh is responsible for developing and executing the Novus business strategy in the region.

“Asia represents a huge opportunity for growth for NOVUS,” says Vaibhav Nagpal, DVM, NOVUS vice president and managing director for Asia. “Manish has extensive expertise about the market and the customers throughout South Central Asia. He also has the confidence of his colleagues to make sound, strategic decisions that will help grow the business in the region. With 15 years of experience working in South Asia and Asia-Pacific regions in various roles, I am sure he will strengthen the NOVUS team and grow the business.”

Dr. Singh says his top priority in the new role is his colleagues.

“I aim to build a culture of trust by fully engaging my colleagues,” he says. “Agriculture is a business about animals and plants, but the foundation is people. It takes many people in many roles working together to produce high-quality, safe, nutritious food. By fostering a collaborative working environment across all my teams, we will be more successful as a trusted partner for all our customers and stakeholders.”

Speaking about the poultry and dairy customers in South Central Asia, Dr. Singh says there are many opportunities for intelligent nutrition from NOVUS to positively impact animal performance and help producers achieve their goals.

“Feed cost is a top concern for producers worldwide. We can help optimize feed costs and affect the impact of anti-nutritional factors through our knowledge about feedstuffs along with our CIBENZA® Enzyme Feed Additive,” he says. “Meat consumption and processing is on the rise; we have solutions for those concerned about meat quality, growth efficiency and structural health. Our team also has global expertise in maternal health that, partnered with the use of MINTREX® Bis-Chelated Trace Minerals, can help optimize the reproductive performance.”

As an international company, Dr. Singh said NOVUS has a dedicated team of in-house technical experts and renowned third-party consultants to support producers as they work to improve gut health and immune system function and implement antibiotic-free production.

“Through an integrated approach combining technical know-how with gut health products like AVIMATRIX® Feed Solution and NEXT ENHANCE® Feed Solution, we are helping create effective ABF production,” he says.

Dr. Singh says following the initial success of the NOVUS dairy team in India, the company has invested more resources, allowing further expansion in this market. The goal is to reach more customers and bring innovative solutions backed by scientific research to the largest dairy market in the world.

“There are many challenges and opportunities in dairy production. NOVUS has decades’ worth of research and commercial trials demonstrating how we can improve milk fat production and reproductive performance,” he says. “On the challenge side, we have products that are shown to reduce somatic cell count and manage lameness to improve productivity and extend the herd’s longevity. This is an important growth market for NOVUS and we have a lot to offer.”

Dr. Singh came to NOVUS in 2019 to serve as the head of strategic marketing and technical services for South Central Asia before leading the marketing team for the Asia-Pacific region. He held roles at Cargill and Alltech before coming to NOVUS.

 

Bentoli Agri Nutrition Pvt Ltd expands reach in Nepal through strategic partnership with Panacea Vet Services Pvt. Ltd.

Bentoli Agri Nutrition Pvt Ltd., a leading provider of specialty additives for animal feed, is proud to announce a new strategic partnership with Panacea Vet Services Pvt. Ltd., one of Nepal’s top distributors in the animal nutrition market. This collaboration expands Bentoli’s access and strengthens its commitment to serving the growing Nepali market. 

The official signing ceremony, held at the end of 2023, was officiated by Dr. Sushanta Saha, Regional Director (SA & SEA) from Bentoli and Mr Baburaj Rawal, Managing Director from Panacea Vet Services. They underscored the importance of this partnership, stating, “This strategic decision reflects our dedication to reaching the dynamic Nepal market more effectively. By joining forces with Panacea, a trusted name with state-of-the-art infrastructure and extensive distribution networks, we can deliver our innovative animal nutrition solutions to even more customers.”

Panacea’s impressive reputation and robust logistics network perfectly align with Bentoli’s mission of fostering animal health and welfare through advanced feed additive solutions. This partnership will enable Bentoli to:

Enhance market reach: Leverage Panacea’s established footprint to efficiently distribute its diverse product range across Nepal.

Streamline logistics: Optimize delivery processes through Panacea’s well-equipped storage facilities and distribution channels.

Meet growing demand: Address the rising demand for high-quality animal feed additives in Nepal’s burgeoning market.

Dr. Sushanta Saha further emphasized, “Our commitment to providing innovative animal nutrition solutions transcends borders. Joining hands with Panacea is another significant step in our mission to offer the best products and services to our valued customers, wherever they may be.”

This strategic partnership marks a new chapter in Bentoli’s expansion plans and underscores its dedication to fostering animal health and welfare globally. With Panacea as its trusted partner, Bentoli is poised to make a significant impact on the Nepali animal nutrition market, benefiting farmers, livestock, and the nation as a whole.

About Bentoli: Bentoli® is dedicated to providing our customers with the highest quality products, services and consultative solutions that will tangibly improve their operational and financial performance.

The company manufactures preservatives, processing and nutritional additives for aqua and animal feeds. It employs a comprehensive and methodical approach to develop optimal solutions for feed manufacturers and farmers. Working closely with feed manufacturers and livestock operators to thoroughly understand their specific
needs, the company uses a consultative, collaborative approach to identify problems, develop solutions and continuously monitor performance to achieve desired results for our customers. It has an active R&D involving labs and animal rearing facilities.

Poultry India 2023 was a great success for Nutrex, and we couldn’t be more proud of our team. It was an amazing few days, and we want to extend a huge thank you to everyone who stopped by our booth to learn more about our company & range of solutions.

Nutrex’s Key Highlights at Poultry India 2023

  • Showcased innovative products: Nutrex showcased its innovative range of feed additives that are designed to improve animal health, performance, and well-being. Including its new range of gut health solutions, such as EndoBan, PhytoStar, Free-Tox and Nutrase BXP. These products are designed to help producers maintain healthy gut flora in their animals, which is essential for optimal nutrient absorption and immune function.
  • Intensive networking : we had the opportunity to meet with customers and partners from all over South Asia at the event, allowing us to discuss our latest products, and to learn more about our customer’s needs.

Nutrex’s Commitment to the Poultry Industry

Nutrex is committed to providing the poultry industry with the highest quality feed additives. We are constantly innovating to develop new products that can help poultry producers improve the health, performance, and well-being of their poultry.

Nutrex at Poultry India 2023

Nutrex’s Impact on the Poultry Industry

Nutrex’s products have a significant impact on the poultry industry. Our feed additives are meticulously formulated to optimize nutrient absorption and utilization, promoting healthier, more productive poultry. This translates into improved meat and egg quality, reduced feed consumption, and a diminished environmental footprint.

Conclusion

Our team of experts provides technical support and guidance to farmers and feed producers worldwide, ensuring that they have the knowledge and resources necessary to optimize animal health, performance, and profitability.

Overall, Nutrex’s participation at Poultry India 2023 was a success. Nutrex was able to showcase its innovative products, meet with customers and partners, and reaffirm its commitment to the poultry industry.

Contact us for more information:

Mr Kurt Van de Mierop (Managing Director)
Mr Geert Van de Mierop (Managing Director)
Dr. Amit Kumar Patra (Technical Sales Manager-SOUTH ASIA) Amit.Patra@nutrex.eu

Nutrex
Hoogbuul 24 • 2250 Olen• Belgium
+32 (0)14 88 31 11
www.nutrex.euinfo@nutrex.eu
https://www.linkedin.com/company/nutrex

Implementation of the hygiene program in a hatchery is not only sufficient to ensure to produce healthy chicks but also is fallow in breeding farm, broiler farm, processing unit, transport. Successful egg incubation and good machinery are two important factors which results in better hatchability and quality of chicks.

Authors
Authors: Dr. Vasudha Kuncham, [Technical Manager, Animal Nutritionist, Veterinary Doctor, MLIT Sol Pvt. Ltd.] and Ms. Sucharita Kumar, [Digital Marketing Analyst, MLIT Sol Pvt. Ltd.]

Maintenance of all critical parameters at optimum levels using technology helps in avoiding manual errors. HRMSC is both real time remote monitoring and smart controlling device which helps in maintaining the criticals precisely leading to better management and minimal errors which in turn leads to improved hatchability and reduced cull percentage. Overall, this machinery helps in improving productivity in hatcheries.

What is hatchery in poultry farming?

The industry that produces and distributes chicks that are one day old through artificial incubation is referred to as a “hatchery.” In simple words hatchery is where the fertilized eggs are incubated, and chicks are hatched before being sent to a farm to be raised for market. Andhra Pradesh tops the chart of poultry production in India followed by Tamil Nadu, Maharashtra, Telangana, West Bengal, and Karnataka.

Hatchery

What should be the location and site for hatchery in poultry farming?

The poultry farms and hatcheries should be in an area which is far away from industrial and residential areas. It should have good ventilation for air and light and basic requirements of water and electricity. The temperature of the environment for the birds should be 22-30 degree Celsius and the relative humidity should be 30-60 %.

  • The distance between the hatchery and the chicken house should be at least 1500 feet (460 metres). The hatchery should be kept far from breeding farms, feed mills, and grain storage facilities, though.
  • The hatchery area should be a distinct building with a separate entrance and exit from the chicken farm.
  • Size of the hatchery is dependent upon the number of chickens to be hatched in each setting or each week based on the local demand or supply of day-old chicks.
  • The rooms need to be set up differently to make greater use of the space available, provide a quicker path for the eggs, and limit employee movement.
  • The structure of the hatchery should allow hatching eggs to be taken in at one end and the chick removed at the other.

What are the main parameters of hatchery management?

Temperature– According to principles of incubation, incubation temperature should be maintained between 99o and 100o Fahrenheit, but the acceptable range is 97o– 102o Fahrenheit. The optimum temperature for chicken egg in the setter (for first 18 days) ranges from 99.50 to 99.75o F and in the hatcher (last 3 days) is 98.50o F.

Humidity– Recommended incubation relative humidity for the first 18 days ranging between 55 to 60% (in setter) and for the last 3 days ranging between 65 and 75% (in the hatcher). Higher humidity during hatching period is given to avoid dehydration of chicks.

Ventilation (Oxygen and Carbon dioxide level and air velocity)- The setter’s air has an oxygen concentration of about 21%. The hatchability decreases by 5% for every 1% decrease in oxygen. The tolerance level of CO2 for the first 4 days in the setter is 0.3%. CO2 levels above 0.5% in the setter reduce hatchability and completely lethal at 5.0%.

Position of eggs– Holding eggs for artificial incubation should be done with the large ends upwards. Eggs are typically laid large end up during the first 18 days (in the setter) and horizontally for the final 3 days (in the hatcher).

Turning of eggs– Eggs should be turned at least 8 times a day. In large commercial incubators the eggs are turned automatically each hour i.e., 24 times a day. Most eggs are turned to a position of 45o from vertical, and then reversed in the opposite direction to 45o from vertical. Rotation less than 45o are not adequate to achieve high hatchability. Turning is not required in hatcher.

Main parameters of hatchery management

What is Hatchery Management?

Implementation of the hygiene program in a hatchery is not only sufficient to ensure to produce healthy chicks but also is fallow in breeding farm, broiler farm, processing unit, transport. All the person who involves in this process should be aware of all measures, facts, and procedures of hygiene. A collective approach is the only way to ensure best hygienic condition in the hatchery.

The most important goal of any hatchery is to introduce the best quality parent flock with the highest hatchability. Therefore, managing the daily operations of contemporary commercial hatcheries is a crucial managerial task. It’s critical to manage machinery and eggs well.

Three primary factors determine the best quality chicks’ maximum hatchability. They are:

  1. Good quality healthy eggs.
  2. Successful egg incubation.
  3. Efficient egg handling equipment and good operation from egg collection on the supply farm to the distribution of chicks from the hatchery.
Diagram of hatcher room with exhaust plenum showing airflow
A diagram of the hatcher room with exhaust plenum showing the direction of air flow (black arrows).

What are the problems in hatchery?

Despite a batch’s success, it must constantly be watched over. It is advised to open eggs that are still in the tray for all batches at least once every two weeks. Since the root of lower birth rates isn’t always identified in the hatchery, it can be challenging to identify the cause in some cases. The issue may have started in the feed factory or be related to the health of the breeders, their management, egg storage and transportation, etc. Additionally, elements such as temperature and humidity may contribute to an anomaly.

The problems that are generally faced in a hatchery are as follows:

1. Broken out eggs.
2. Chicks hatch late.
3. Death of chicks.
4. Reduced growth of chicks.
5. Weak chicks.
6. Exposed brain.
7. Crooked toes and spraddled legs.
8. Loss of water from eggs.
9. Short or missing beak.

Why are the hatcheries in poultry industry lagging?

How much ever we try to technologically become strong, we must remember that we are still lagging in the fields of animal husbandry. Till today, we face difficulty in proper management, marketing, transportation, and basic facilities.

Every hatchery strives to generate the greatest number of good quality birds from viable eggs. Analysing the eggs that are still in the trays is one of the most effective methods for achieving this goal. A chick may fail to free itself of the shell for many reasons. They include chick strength, chick position, air cell position, disrupted hatch, and improper incubation humidity.

Have you ever thought what can be the solution to these many problems? It is high time we should start thinking on these factors to prevent anymore losses.

MLIT PoultryMon has the perfect device which can be the solution to all these problems. The Hatchery Remote Monitoring with Smart Controller (HRM-SC) is a supernova solution which provides real time remote monitoring of temperature, humidity in the hatchery along with several other parameters like rack turning, fan rpm/speed, power supply and door condition. The gateway sends cumulative information from about 30 HRM devices to the cloud. The smart controller controls the criticals in the incubator with fully integrated alarm management, alerts automatically and detects changes to temperature, humidity, fan rotation, malfunctioning, door open or power loss in setters and hatchers.

As a result, we can see 1-2% reduction in risk, 1-2 % increase in hatchability, 30-50% reduction in cull percentage, reduction in 3% of electricity consumption, improved quality and quantity of the chicks, better labour management and bird welfare.

For more information, email info@mlitsol.com, website: www.poultrymon.com


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Introduction: In the world of poultry farming, two significant concerning factors are litter ammonia and relative humidity. The presence of ammonia gas released by uric acid decomposition in bird droppings is referred to as the litter ammonia level. High quantities of litter ammonia may negatively impact the respiratory system, eyes, and feet, resulting in decreased production and increased mortality rates. Relative humidity, on the other hand, refers to the amount of moisture in the air. Maintaining adequate humidity levels is critical for preventing pathogen growth and infection.

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Poultry excreta comprises undigested feed protein and uric acid, which microbial enzymes convert it to ammonia (NH3). Several litter characteristics influence this conversion, including pH, temperature, oxygen, moisture concentrations, and substrate availability. The recommended limit for ammonia in a chicken shed is less than 10 ppm, however, up to 25 ppm is not detrimental. Ideally, the relative humidity should range between 50 and 70%. The rainy season, defective foggers, insufficient ventilation, water leaks, and other factors all contribute to increased humidity inside the shed.

Ammonia levels and humidity in poultry houses are interconnected. High relative humidity can exacerbate the adverse effects of high blood ammonia levels in poultry. In humid environments, more NH3 may be dissolved in the air droplets and inhaled into the blood during respiration by birds, consequently increasing the blood ammonia content. When ammonia gas is exposed to moisture, it reacts and forms a corrosive solution called ammonium which causes harm to birds. Additionally, high humidity can hinder the evaporation of moisture from the litter, causing it to retain more ammonia.

Deleterious Effects on Poultry:

  1. Respiratory Issues: High levels of ammonia in the poultry house air can cause respiratory problems to the birds. Ammonia gas affects the trachea’s mucosal surface, causing paralysis of cilia, sometimes deciliation of epithelial cells, and causes necrosis of the mucosal epithelium.
  2. Foot Lesions: The constant exposure of poultry to ammonia can cause severe foot lesions by causing chemical burns on the foot pads of birds, leading to painful and debilitating footpad dermatitis.
  3. Eye Lesions: High concentrations of atmospheric ammonia for a prolonged duration causes irritation, conjunctivitis, and damage to the cornea of the eyes. Swelling and reddening of the eyelids, irritation, reddening of the conjunctiva and nictitating membrane, and partial or complete closure of the eyes are common clinical signs.
  4. Reduced performance.

How to prevent it:
Along with farming management like dietary management, stocking density, proper ventilation, house temperature, litter management, etc., other supplements like Phytogenic Feed Additives can be supplemented in a poultry diet. A phytogenic feed additive reduces the gut inflammation caused by stressors and maintains gut integrity, resulting in better nutrient digestibility in birds. In addition, it helps to maintain the homeostasis between beneficial and harmful gut microflora which would minimize the adverse effect of harmful bacteria on the gut. This ultimately leads to a reduction in the excretion of undigested and unabsorbed nutrients through feces from a healthy gut, which means less nitrogen excretion.

STODIStandardized Polyherbal Formulation containing fruit rinds of Punica granatum, aerial parts of Andrographis paniculata, bark of Acacia nilotica, fruits of Terminalia bellirica, and bark of Holarrhena antidysenterica has shown to be an effective solution for loose dropping. In various studies, it has been found that supplementation of this polyherbal formulation has significantly reduced litter nitrogen (g/100g of litter) as compared to the group without supplementation. Phytogenics of this polyherbal formulation (PHF) maintains the gut integrity and peristalsis movement of the gut which increases the time for the protein and other nutrient utilization by the birds. This increased protein utilization leads to reduced excretion of nitrogen which in turn decreases the production of ammonia levels in litter. Along with this PHF has been shown to improve the gut microbiota level and gut immunity of the bird poultry.

In conclusion, the combined impact of ammonia and humidity in the world of poultry farming underscores the critical importance of maintaining a balanced and controlled environment for the well-being and productivity of the birds. High ammonia levels in poultry houses can lead to a range of deleterious effects. Phytogenics of polyherbal formulation have been shown to reduce the ammonia level in litter with improved nutrient utilization and gut microbiota balance.

Authors:

References
Chigwada, J., Mazunga, F., Nyamhere, C., Mazheke, V. and Taruvinga, N., 2022. Remote poultry management system for small to medium scale producers using IoT. Scientific African, 18, p.e01398.
Sheikh, I.U., Nissa, S.S., Zaffer, B., Bulbul, K.H., Akand, A.H., Ahmed, H.A., Hasin, D., Hussain, I. and Hussain, S.A., 2018. Ammonia production in the poultry houses and its harmful effects. Int. J. Vet. Sci. Anim. Husb, 3(4), pp.30-33.
Weaver Jr, W.D. and Meijerhof, R., 1991. The effect of different levels of relative humidity and air movement on litter conditions, ammonia levels, growth, and carcass quality for broiler chickens. Poultry science, 70(4), pp.746-755.

The poultry industry in India has witnessed significant growth over the years, making it one of the largest contributors to the country’s agriculture sector. Poultry farming has become a source of livelihood for many, and it plays a crucial role in providing a steady supply of eggs and meat to the growing population. However, as the poultry sector continues to expand, it faces a pressing issue that threatens the health and well-being of the birds and the livelihoods of poultry farmers. Loose dropping is one of the common diseases affecting poultry health and production. Loose droppings involve the excretion of loose, unformed faeces by the birds, which is often accompanied by increased water content and a lack of consistency.

Authors STODIOne of the most challenging aspects of addressing loose droppings in poultry is the non-specific nature of the causes. Unlike specific diseases or pathogens that can be easily identified and targeted, loose droppings may be triggered by a range of factors, making diagnosis and treatment complex. The non-specific causes of loose dropping involve management, environment, metabolism, and nutrition.

Environment and temperature one of the pre-disposing factors responsible for the occurrence of loose dropping in poultry. When birds are exposed to high temperatures inside the shed, it can cause stress in them and cause them to drink more and eat less to regulate their body temperature. Furthermore, it has been demonstrated that heat stress damages intestinal integrity and leads to a leaky and inflammatory gut. Loose dropping will result from less intestinal water absorption due to compromised gut integrity. Whereas in low temperatures and high humidity, poultry tends to eat more and reduce water intake. A reduction in water intake can be an indication of dysbacteriosis. The ventilation systems in a chicken house are intimately related to the ammonia content there. Poor ventilation causes poultry houses to have excessive levels of ammonia, which is a common problem during winter. In the poultry house, an ammonia level of more than 25 ppm has a negative impact on the health and productivity of the birds. High levels of ammonia can interfere with normal organ function, hinder energy metabolism, promote cell apoptosis, and harm the mitochondria in the mucosa of the digestive system.

Nutrition plays a pivotal role in the occurrence of loose dropping in poultry. Due to frequent fluctuations in feed prices, poultry farmers are looking for alternative ways to balance the ration. A variety of antinutritional elements found in alternative feed sources, whether they are protein- or energy-based, impact gut integrity and feed digestion, resulting in loose dropping. Numerous factors, such as a diet rich in non-starch polysaccharides, Distiller’s dried grains (DDGS), soyabean meal (SBM) quality, low-quality fat, and high salt and minerals, etc, contribute to loose dropping in poultry.

SBM contains several antinutritional elements that could alter intestinal homeostasis and reduce poultry’s ability to utilize nutrients. The main anti-nutritional factors in SBM, are trypsin inhibitors. According to reports, the quantity of trypsin inhibitors in the diet is directly connected with outbreaks of rapid feed passage in broilers. High trypsin inhibitor levels in soybean meal are an indicator that the processing conditions were not ideal for reducing trypsin inhibitor content in raw soybeans from about 40 mg/g to a concentration of around 2 mg/g in soybean meal.

The economic impact of loose droppings on poultry farms is considerable. Poultry farmers face financial difficulties because of decreased growth rates, increased mortality, and higher feed and medicine expenditures. Considering these challenges, poultry farmers must implement strategies to mitigate the effects of loose droppings. In order to lessen stress on the birds, this requires maintaining optimal environmental conditions. To reduce the likelihood of loose droppings, it’s essential to maintain high-quality, balanced food and closely monitor the water supply. Furthermore, various phytogenic feed additives have also been shown to lessen the possibilities of loose dropping in poultry. The active ingredients found in natural preparations are classified as plant secondary metabolites (PSM) and can have a wide range of biological effects on an animal’s body. Depending on their concentration and combination, they may have antibacterial, anti-inflammatory, as well as antioxidant properties.

STODISTODI a pure phytogenic formulation, supports in prevention of non-specific loose droppings in poultry. STODI is composed of Andrographolide, punicalagin, polyphenols, and ellagitannins which work synergistically to prevent loose dropping in poultry. In a study conducted on rats, it was found that castor oil-induced diarrhea was significantly reduced. Also, the intestinal transit was inhibited by up to 33% and the weight of secretory contents induced by castor oil was significantly reduced by polyherbal formulation, approximately 29% in the enterpooling assay. In another study conducted in Ross 308 broiler chicks, were treated with magnesium chloride in the negative control group whereas the STODI group contained magnesium chloride along with STODI. It was found that supplementation of STODI was effective in modulating the caecal microbial population in a manner conducive to gut health and performance of broilers, as revealed by the increase in abundance of favorable microflora. STODI has also proven that a wet litter broiler model was developed through excessive feeding of MgCl2, which caused the performance parameters to worsen, and the emergence of problems associated with the wet litter. Supplementation with STODI ameliorated these problems and, therefore, it can be used for the management of wet litter in poultry by its properties of augmenting gut integrity, anti-inflammatory effects on the intestinal lumen, check hyper-secretion, normalizing gut peristalsis, enhancing gut immunity and improves microbiome.

In conclusion, the poultry industry in India has seen remarkable growth, playing a pivotal role in meeting the country’s increasing demand for poultry products. However, the emergence of loose droppings in poultry flocks is a complex challenge that threatens the health of birds and the livelihoods of poultry farmers. The economic impact of loose droppings on poultry farms is substantial, causing reduced growth rates, higher mortality rates, and increased costs associated with feed and medication. To mitigate these challenges, poultry farmers must adopt a multifaceted approach, the use of phytogenic feed additives like STODI has shown promise in supporting the prevention of non-specific loose droppings in poultry.

References:
  • Dunlop, M.W., Moss, A.F., Groves, P.J., Wilkinson, S.J., Stuetz, R.M. and Selle, P.H., 2016. The multidimensional causal factors of ‘wet litter’in chicken-meat production. Science of the Total Environment562, pp.766-776.
  • Hermans, P.G., Fradkin, D., Muchnik, I.B. and Morgan, K.L., 2006. Prevalence of wet litter and the associated risk factors in broiler flocks in the United Kingdom. Veterinary Record158(18), pp.615-622.
  • https://www.biomin.net/science-hub/5-tips-to-successfully-manage-poultry-house-ammonia-levels/#:~:text=Optimize%20the%20poultry%20stocking%20density,temperature%20of%20the%20poultry%20house.
  • https://www.poultryproducer.com/wet-droppings-or-diarrhea/#:~:text=Excessive%20water%20intake%20has%20a,to%20regulate%20their%20body%20temperature.
  • Makwana, R.B., Savsani, H.H., Chavda, M.R., Odedra, M.D., Garg, D.D., Ribadiya, N.K., Karangiya, V.K., Vaghamashi, D.G., Chavda, J.A. and Belim, S.Y., 2022. Constraints and amelioration of non-starch polysaccharides (NSP) in broiler diets: A review.
  • Marimuthu, S., Balasubramanian, B., Selvam, R. and D’Souza, P., 2019. Evaluation of a polyherbal formulation for the management of wet litter in broiler chickens: Implications on performance parameters, cecal moisture level, and footpad lesions. Journal of Advanced Veterinary and Animal Research6(4), p.536.
  • Marimuthu, S.K., Balasubramanian, B., Selvam, R. and D’Souza, P., 2019. Modulation of chicken cecal microbiota by a phytogenic feed additive, STODI®: a metagenomic analysis. Pharmacognosy Research11(3).
  • Murugan, S., Purusothaman, D., Richard, E.J., Chalichem, N.S.S., Bethapudi, B., Chandrasekaran, P.R., Velusami, C.C., D’Souza, P. and Mundkinajeddu, D., 2020. Anti-diarrhoeal activity of a polyherbal formulation in rats and elucidation of its cellular mechanisms. Avicenna journal of phytomedicine10(4), p.417.
  • Sheikh, I.U., Nissa, S.S., Zaffer, B., Bulbul, K.H., Akand, A.H., Ahmed, H.A., Hasin, D., Hussain, I. and Hussain, S.A., 2018. Ammonia production in the poultry houses and its harmful effects.  J. Vet. Sci. Anim. Husb3(4), pp.30-33.

 


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