Synopsis: CRD & CCRD is a severe & chronic yearlong/anytime infection in all age groups of poultry Poultry Farmers can be victorious and at their ease by overcoming this stubborn infection with the scheduled CRD – C-CRD prevention program with the effective usage of anti-mycoplasma solution through feed and/or through drinking water.

CRD – Round the clock with infection

CRD infection is caused by Mycoplasma gallisepticum (MG).

When MG gets complexed it forms C-CRD – Complexed CRD with either of the following reasons

1. C-CRD of Bacterial Infection – MG with Escherichia coli (E. coli) infection

2. Environmental C-CRD MG with contaminated air (High ammonia level)

3. Viral infections – MG with Viral Infection

C CRD 

Complexed-CRD (CCRD) is caused by the stubborn infection of Mycoplasma Gallisepticum (MG) ‘clubbed with either E. coli/Ammonia/Viral infection.

CCRD can affect all formats of poultry in anytime in all formats of Poultry in any age- Broiler, Layer & Breeder
It’s highly prevalent during extreme weather conditions like summer or winter.

However, CCRD is round the clock infection with low mortality and high morbidity, which can suppress immune system of the birds.

Sub-clinical level infections are frequent which can cause severe Production loss with high feed intake & low production.

Acute infections can cause an outbreak.

Birds’ Respiratory system – A complex one

CCRD -Complex CRD – CCRD is crucial & vulnerable when MG combines with respiratory infections in Poultry.

Bacterial CCRD – MG + clubs with Bacteria – E. Coli to form Colibacillosis.
Symptoms

• Diarrhoea
• High Feed consumption & High mortality if not treated well in time

Non infectious CCRD MG with contaminated air (Ammonia Gas)
This CCRD causes ‘Acidic blood’.

Birds’ Excessive inhalation of Ammonia & Low oxygen intake, increase the levels of Carbonic Acid in the blood causing Acidic Blood condition.

Symptoms

• Panting, High-water intake, crowding (hurling together)
• Feather loss, High stress & Sudden deaths

Viral C-CRD – MG + Viral infection (ILT & IB are common)
MG clubs with ILT – Infectious Laryngotracheitis virus & IB (Infectious Bronchitis) – Common.
MG with other viral infections of Avian Influenza, New castle disease & Infectious Coryza

CCRD – Disease Stages

CCRD Stage 1 – CCRD infects Trachea – URT –Upper Respiratory Tract infection

CCRD Stage 2 – Forms Septicaemia – CCRD Infection spreads into Circulatory system

CCRD Stage 3 – Airsacculitis – CCRD Infection becomes intense & Chronic when it gets deep into the LRT – Lower Respiratory Tract

CCRD Stage 4 with clinical symptoms
There will be notable clinical symptoms of coughing, swollen eyes, noisy & difficulty in breathing, change in colour of the comb – blackish red, severe production loss in laying hens with high feed intake.

With the above clinical symptoms, if CCRD is not treated properly can lead to severe economic losses including acute mortality (sudden deaths of the birds).

CRD & C-CRD – Prevention Program

They are better to control than to treat through feed & through drinking water.

Broiler, Layer & Breeder –

The choice of drug to prevent mycoplasma infection – Macrolide group of antibiotics.

Administration – Through feed.

For treatment to control the mortality

• Macrolide and/or Aminoglycoside group of antibiotics
• Can be administered through feed, water & through injection (s/c sub cutaneous injection and adult birds through I/M – Intra Muscular)

Dosage can be followed as per the advice of the consulting vets

Complimenting the CRD – C-CRD Prevention program

This Prevention program can be double assured by clubbing the alternative medicines

• Phytochemical solutions as extracts – Gingerol, Curcumin, Solanum trilobatum as expectorants, immune booster and blood purifier.
• Essential oils combination – can be administered through drinking water.
• Acidifier through feed and or drinking water.
• Permitted AGPs

AGPs dosage can be followed by the consulting vets’ advice.

Withdrawal of AGPs should be strictly followed to ensure food safety measures.

Summary

CRD & C- CRD (MG – Mycoplasma gallisepticum) infection can cause great economic losses if not attended properly.

However, CRD & C-CRD infection can be prevented & cured in all formats of poultry (Broiler, commercial Layer & breeder) with systematic usage of combination of Anti-mycoplasma drugs with the alternative medicines ‘discussed here.

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